So I'm not a heavy-duty tweeter. But I do have a twitter account, so every once in a while I'll look at the twitter software for the Mac.
My main app for the moment is TwitterPod. It's a program from Japan that supports Sparkle and Growl and spell check and provides a search function for all of those tweets. It provides for templated tweets, such as waking up and eating dinner and all of the routine matters that are tweeted. It also provides some integration with the web browsers, such as opening the URL from a tweet ...